I ran an MDS (multi displacement system) engine for 2 years before dumping it (2005 Hemi). 10% mpg gains is an overstatement; its 10% while it engaged, which is only when cruising under no load. How much actual no load cruising you do? Its probably a lot let than you think. Bottom line for me was it was a marketing and EPA appeasement effort that has very little to do with the real world.
As for the tech... I wonder what this does to the ECU itself. I mean, as far as the O2 sensor is concerned, your engine is running lean now right? You've got 4 cyl worth of fuel being burned instead of the 8 its used to seeing, everything else being equal? So does that mean the ECU will richen up the mix dumping more fuel into the cyls that are still "on"? Meaning you end up burning at least as much gas as before, if not more?
Or how about misfire codes? What about the knock sensors?
Sure is starting to smell like snake oil around here...