two things that helped me, You have to hold/push the large hose all the way into the intercooler fitting and tighten at the same time, making sure that the hose clamp does not tighten at an angle or tighten on the edge of the flange of the intercooler. Secondly, tighten the hose clamp at the top of the large hose, while making sure you are holding the piping in place and the hose clamp is tightening evenly on the hose. I rotated all the clamps for the large hose so they pointed towards the center of the truck and used and socket extension to tighten from underneath the truck. For the blue hoses, rotate/turnaround hose clamps so they point to the center of the truck and you can tighten with a socket extension from underneath the truck. You really have to crank down on the hose clamps
I don't personally have lighting in the grill like you, however I don't think you'd have any issues. The Titan isn't exceptionally tall and doesn't protrude above the bottom of the grill (like the Wagner unit for example).