128,700 here, only relatively minor problems for me:
-Sunroof had a piece of the guide break, locked it in place and no leaks.
-AC Blend door on passenger side went out (Not an easy task to replace, but $35 or so for the part)
-Broken wire on the plug for one of my fuel injectors (10 min fix)
Basically nothing I've had to put big money into. Sunroof took me about 8-10 hours on a saturday to take apart and lock into place. AC Blend doors were about a 4.5 hour job with a buddy helping me pull the dash. The wire was just simply buying a new electrical connector and soldering it in.
I beat on mine pretty hard and I've got to say, they're pretty solid trucks.